TY - JOUR T1 - Safety and Efficacy of Atropine on the Labor Progress TT - بررسی ایمنی و پیشرفت مراحل زایمانی آتروپین JF - KAUMS JO - KAUMS VL - 9 IS - 1 UR - http://feyz.kaums.ac.ir/article-1-157-en.html Y1 - 2005 SP - 35 EP - 39 KW - Atropine KW - Labor progress KW - Bishop score of cervix N2 - Background: Despite wide use of Atropine by midwives and physicians as an adjunct to labor, obstetric literature contains few references to this effect of the drug. This study was a double blind, randomized controlled trial of primigravidas in Iran to determine the safety and efficacy of Atropine on the labor progress. Materials and Methods: One hundred primigravidas in uncomplicated spontaneous labor, cervical dilation less than 4 cm and cervical effacement less than 50% were randomly assigned into two groups: the experiment group (N=50) receiving 0.5mg Atropine and the control group (N=50) receiving placebo, with predetermined codes, single dose injected at the beginning of the active phase of labor. The groups were compared for Bishop score of cervix after 1 h of injection, duration of active phase of labor, duration of second stage of labor, Fetal tachycardia and bradycardia 0.5 and 1 hours after injection, Apgar score and birth weight. The accepted level of significance was P M3 ER -