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Showing 3 results for Rostami
Asieh Abbassi-Daloii , Ahmad Abdi, Hoda Yazdani-Tapesari , Mojtaba Salehpour, Zahra Rostami-Angasi , Behroz Yahyaei ,
Volume 20, Issue 2 (Bimonthly 2016)
Abstract
Background: Evidence supports the systemic inflammation in obesity and insulin resistance. Apelin is secreted by adipose tissue and plays an important role in the inflammation process. The present study aimed to examine the effect of 8 weeks aerobic training on plasma Apelin in male rats treated with Nitro-L-Arginine-Methyl Ester (L-NAME).
Materials and Methods: In this experimental study male Wistar rats (n=24, age 20 months) were randomly assigned into four groups: Control, Training, TrainingS+L-NAME and L-NAME. An aerobic training protocol was performed for eight weeks, 5 times a week with an intensity of 75-80% of maximal oxygen consumption. The rats were sacrificed 72 hours after the last exercise session and blood samples were collected. Data were analyzed by ANOVA and Tukey post hoc test at P<0.05 significancy level.
Results: The results showed that plasma Apelin level did not change significantly after eight weeks of aerobic training compared to the Control group. However, the results showed that there was a significant difference in plasma Apelin between L-NAME and Control group (P<0.003). In addition, the results showed no significant difference between the insulin level and glucose in four groups.
Conclusion: It seems that with increasing age plasma Apelin level is not affected by aerobic exercise. However, nitric oxide inhibitors can reduce the plasma Apelin level.
Niloofar Sadatrostami Arjmand, Farshad Ghazalian, Ali Sharifnejad,
Volume 25, Issue 4 (Bimonthly 2021)
Abstract
Background: Exercise at different intensities can provide effective stimuli for the adaptation of brain function, because the activation of the cerebral cortex is sensitive to the frequency of movement. Therefore, the aim of this study was to evaluate the effect of six weeks interval training on brain waves and electrical activity of the cerebral cortex in healthy young girls.
materials and methods: In this quasi-experimental study, 10 young girls with an age range of 20-30 years who had no history of exercise and interval training were randomly selected and performed interval training for six weeks (three sessions per week) with an intensity of 40-50% of maximum heart rate. they did. Alpha and beta brain waves were measured before and after six weeks by electroencephalography. Then the data were analyzed using paired t-test and SPSS software version 21 at a significance level of p≤0.05.
Results: Analysis of data using paired t-test showed that the amount of changes in alpha and beta brain waves after six weeks of interval training in the post-test was significantly different from the pre-test (p = 0.001)
Conclusion: Based on the present results, it can be concluded that regular exercise may cause positive changes at the level of the cerebral cortex (electrical activity). Therefore, the interval training protocol can be an effective intervention to improve brain waves and electrical activity of the cerebral cortex and potentially promote brain health.
Parvin Hojati, Mehdi Rahnema, Ali Rostami, Hossein Mostafavi,
Volume 26, Issue 5 (Bimonthly 2022)
Abstract
Background: Cinnamon improves the lipid profile and has antioxidant and protective effects. Therefore, in this study, the effect of cinnamon on the expression of NKCC1 and KCC2 genes in the stroke model of rats receiving a high-fat diet (HFD) was investigated.
Materials and Methods: Thirty-six rats were divided into four groups: control, model (stroke), cinnamon 130 and 260 mg. All groups, except the control group, received HFD for 8 weeks, and then the groups receiving cinnamon were injected with 130 and 260 mg/day of cinnamon for 6 weeks, respectively. The animals were anesthetized and stroke was induced in them with middle cerebral artery occlusion model. After 12 hours, the animals were assessed for body mass index (BMI), stroke volume and expression of NKCC1 and KCC2 genes. One-way ANOVA was used to analyze the data at a significance level of P<0.05.
Results: HFD increased BMI. Cinnamon extract decreased BMI and reduced stroke volume compared to the model group. Decreased expression of NKCC1 and increased expression of KCC2 were significant in stroke hemispheres compared to the model group. The low dose of the extract had a better effect in reducing the expression of genes.
Conclusion: It seems that cinnamon, as a pre-treatment, has valuable and reducing effects on BMI and ischemic strokes caused by obesity, and by modulating the expression of KCC2 and NKCC1 genes, it maintains chlorine ion homeostasis and therefore, it can be considered as a suitable option for the pre-treatment of stroke.
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