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Showing 2 results for Nosrati
Amir Nosrati, Babisan Askari, Masoumeh Habibian, Volume 27, Issue 1 (Bimonthly 2023)
Abstract
Background: One of the important goals of therapeutic interventions is to control obesity and vitamin D deficiency, which are associated with the occurrence of cardiovascular disease, metabolic disorders and increased homocysteine. In this study, the effect of high-intensity interval resistance training (HIIRT) and vitamin D on homocysteine and total antioxidant capacity (TAC) levels in overweight women with vitamin D deficiency was investigated.
Materials and Methods: In this clinical trial study, overweight women with vitamin D deficiency were investigated. The subjects were randomly divided into four groups of 13 (control, exercise, vitamin D and exercise+vitamin D). The exercise groups performed HIIRT with an intensity of 80% of one maximum repetition, and the vitamin D groups consumed vitamin D once a week. The collected data were analyzed using one-way analysis of variance and paired t-tests.
Results: After 8 weeks of research interventions, homocysteine level decreased and TAC significantly increased in the experimental groups (P<0.001). In addition, combined intervention was associated with more changes in homocysteine and TAC levels compared to HIIRT and vitamin D intervention (P<0.001), but HIIRT and vitamin D had a similar effect on the changes of these variables (P>0.05).
Conclusion: It seems that part of the optimal effects of HIIRT and vitamin D consumption in the health development of overweight women with vitamin D deficiency can be induced by increasing TAC and decreasing homocysteine.
Mousa Khalafi, Amir Ghanbarpour Nosrati, Razieh Sadat Mostafavi, Fatemeh Hosseini Jebeli, Volume 27, Issue 4 (Bimonthly 2023)
Abstract
Background and Aim: Growth differentiation factor 15 (GDF15) is a cytokine with anti-inflammatory effects, which the influences of acute and chronic exercise on it are not clearly known. Therefore, the aim of the present meta-analysis was to determine the effect of the acute and chronic exercise on circulating GDF15.
Methods: To extract original articles published in Farsi and English language journals, a comprehensive search was conducted in PubMed, Web of Science, Scopus, Magiran, Noormags and SID databases until December 22, 2022. Two separate meta-analyses were performed to calculate the effect size of standardized mean difference (SMD) and 95% confidence interval for the acute and chronic effects of exercise on GDF15.
Results: A total of 18 studies including 551 subjects were included in the meta-analysis. The results showed that acute exercise activity leads to a significant increase in GDF15 [P=0.001, (1.65 to 0.80 CI: 1.23)], while chronic exercise activity had no significant effect on GDF15 [P=0.24, (0.96 to 0.24-CI: 0.35)].
Conclusion: Exercise leads to a transient and short-term increase in GDF15, which may contribute to the beneficial metabolic effects of exercise.
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