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Showing 2 results for Khoshdel
Fakhrodin Naghibalhossaini, Zahra Khoshdel, Mostafa Moradi , Shahla Shojaei, Abbas Ghaderi, Volume 16, Issue 7 (Supplement 2013)
Abstract
Background: In recent years, measurement of the trace elements in human serum has been used for cancer diagnosis. The purpose of this study was to compare the serum concentrations of Cu, Zn and Cu /Zn ratio of colorectal cancer (CRC) patients with those of healthy subjects. Materials and Methods: This study was conducted on 130 patients with CRC (57 women and 73 men) and 128 health subjects (65 women and 63 men). Flame atomic absorption spectroscopy method was used to analyze the serum trace element concentrations. Results: The results showed that the serum Cu levels were significantly lower (P<0.01) in patients with CRC than the healthy controls, but no significant difference was observed between serum concentration of zinc in patients and healthy subjects. The concentrations of Zn in patients and healthy subjects were (68.38±44.76 vs. 142±37.61 ug/dl) and (84±53.51 vs. 140.37±63.43), respectively, in female and male subjects. Serum concentrations of Cu were (139±139.92 vs. 160.44±46.38 ug/dl) and (123.50±77.76 vs. 160.93±44.15 ug/dl), respectively, in female and male subjects. However, the Cu/Zn ratio increased significantly in both male (2.64±2.98 vs. 1.42± 0.88) and female (3.02±3.90 vs. 1.22±0.60) subjects. Conclusion: The serum copper levels and the Cu/Zn ratio may have an instrumental role in CRC development or can be used as a prognosis marker.
Poneh Mokarram, Hajar Jaberi, Zahra Khoshdel , Behnoosh Miladpour, Fatemeh Ramezani , Mohammad Ali Fahmidehkar, Bahram Movahedi , Volume 16, Issue 7 (Supplement 2013)
Abstract
Background: Gold standard method for the measurement of Magnesium is the atomic absorption spectrophotometery. Studies are shown that Magnesium concentration can also be measured by photometric assay. Therefore, the purpose of this study was to compare the two methods for Magnesium measurement in the patient’s serum. Materials and Methods: Forty diabetic patients (10 men and 30 female) participated in this study. Mean age of the patients was 52.52±4.88. Magnesium was measured in serum by the atomic absorption spectrophotometric and photometric methods (Pars Azmun Kit, using Xylidyl Blue, wave length=546 nm) and then the results were compared. Results: The mean values for the photometric and spectrophotometric methods were 3.03±0.82 and 3.07±0.42, respectively. No significant difference was seen between the two methods (P=0.7). Conclusion: Considering the lower cost and accessibility of using the photometric method, this method, as a reliable method, can be recommended to measure the level of Magnesium.
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