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:: Search published articles ::
Showing 3 results for Khara

Pedram Jarf, Khoshkhoo, Khara, Babaei,
Volume 16, Issue 7 (Supplement 2013)
Abstract

Background: Fish as well as other aquatic animals have become an important source of protein diets. Heavy metals due to their specific physical and chemical characteristics as well as their side effects on various ecosystems are considered as a major contaminator of marine environments.This study aimed to determine the magnitude of heavy metals (Cu, Pb and Cd) in muscle tissues of fish Perca fluviatilis from Amirkolaye wetland in Guilan province.

Materials and Methods: The heavy metals were extracted from the fish muscle tissue by the wet digestion methods (nitric acid and perchloric acid). Moreover, the concentrations of the heavy metals were determined using the flame atomic absorption spectrophotometer (FAAS).

Results: The results indicated that the average concentration of heavy metals Cu, Pb and Cd in the muscle tissues of Perca fluviatilis were 0.475±0.03, 0.035±0.005 and 0.28±0.04µgg-1d.w, respectively.

Conclusion: The concentrations of heavy metals in the fish muscle tissue were lower than the allowable standards of WHO, UK (MAFF), NHMRC and FDA.


Sara Shahbazi , Jaleh Khoshkho, Hossein Khara, Hadi Babaei,
Volume 16, Issue 7 (Supplement 2013)
Abstract

Background: Nowadays, an accumulation of heavy metals in the environment is one the most important consideration in the world. Heavy metals due to their chemical stability, low flexibility and power of bioaccumulation in the body organism are becoming quickly toxic pollutants. This study was carried out to determine the heavy metals (e.g. Cadmium, Copper, Zinc and Lead) in the water and sediments of Amirkolayeh wetland in Guilan from Winter 2010 to Spring 2011 then they were compared to global scales.

Materials and Methods: Sampling was done at the three stations in Amir kolayeh wetland during Winter and Spring. At first, samples were dried by the wet methods and mixed acid then the chemical annualized were done. Concentrations of the heavy metals were determined by a flame atomic absorption spectrophotometer (FAAS).

Results: Results showed that the mean concentrations of heavy metals in water for Cu, Pb, Cd and Zn were 0.394±0.078, 0.03±0.007, 0.011±0.003 and 0.517±0.09mg/l and in sediments were 9.256±1.65, 0.626±0.12, 0.59±0.31 and 44.35±7.44mg/g, respectively.

Conclusion: The results of this study reveal that the heavy metal accumulation increases during the Spring season. Also, the order of the heavy metal accumulation in water and sediment was Zn>Cu>Pb>Cd. On the other hand, the concentrations of heavy metals in water and sediment were lower than the allowable international standards.


Khatere Kharazmi, Azhdar Heydari, Abolfazl Ardjmand,
Volume 23, Issue 1 (Bimonthly 2019)
Abstract

Background: Curcumin, as a polyphenolic compound in turmeric plant, has a neuroprotective effect in the improvement of learning and memory. Curcumin has interaction with diverse molecules, e.g., nitric oxide (NO). The present study dealt with the effect of curcumin pre-treatment on morphine-induced inhibitory memory impairment and nitric oxide metabolites (NOx) level in rat.
Materials and Methods: In this experimental study, rats (n=40) were divided into four groups (each group, 10 rats) and their memory was evaluated in an inhibitory memory apparatus: Control (saline gavage for 35 days+post-training saline (i.p.)); Curcumin (curcumin gavage (10 mg/kg for 35 days)+post-training saline (i.p.); Morphine (saline gavage for 35 days+post-training morphine (7.5 mg/kg/i.p.)); Curcumin+Morphine (curcumin gavage (35 days)+post-training morphine (i.p.)). In all groups, the memory of animals in the second day (test) was reported as the time delay (Sec.) to enter the dark chamber. The locomotor activity was evaluated using the open field. After behavioral tests, the brain of animals was removed under deep anesthesia for evaluating the NOx level using the Griess method.
Results: The time delay to enter the dark chamber in Morphine and Morphine+Curcumin groups were decreased (P<0.001) and increased (P<0.01), compared to Control and Morphine groups, respectively. Tissue NOx levels in Morphine and Morphine+Curcumin groups were decreased (P<0.05) and increased (P<0.001), compared to Control and Morphine groups, respectively. Locomotor activity in open field did not show a significant difference in four groups (P>0.05).
Conclusion: Curcumin improves the morphine-induced inhibitory memory impairment in rat, probably via the NO signaling pathway.


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