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Showing 2 results for Dargahi
Zarebavani, Einollahi , Dashti, Mohebali, Rezaeian , Dargahi,
Volume 16, Issue 7 (Supplement 2013)
Abstract
Background: Trace elements regulate the key metabolic pathways, modulate the immune response, and suppress the incidence of various diseases. The most important vital elements in human body are Copper and Zinc. Zinc is necessary for the immune system functions. Zinc deficiency is associated with acute diarrhea. Copper is essential for the production of red blood cells, hemoglobin formation and absorption of iron, and for the activity of various enzymes. However, the association between trace elements and giardiasis has rarely been investigated. The aim of this study was to measure the serum levels of Zinc and Copper in individuals with giardiasis in comparison with the normal subjects. Materials and Methods: Stool samples were collected in sterile clean stool cups from all volunteers. Examination of fecal samples for detection of Giardia cyst and/or trophozoite was carried out using the direct wet smear and formol-ether concentration method. Among these volunteers a total of 49 positive individuals for Giardia lamblia were enrolled as the study group. The control group consisted of 39 age and sex matched healthy volunteers. Serum was obtained from both groups and kept in-70 0 C freezer for biochemical laboratory examination. Zinc and Copper levels were measured by Diagnostics Kit and colorimetric endpoint-method. Results: Zinc levels in the study group was remarkably lower than the control group (P=0.001). In addition, there was a significant difference in serum copper levels between both groups (P=0.003). Conclusion: Giardiasis elevated the serum copper levels, while it decreased the serum zinc.
Zahra Dargahi, Ali Reza Partoazar, Shima Naddafi, Mohammad Mehdi Soltan-Dallal,
Volume 23, Issue 5 (Bimonthly 2019)
Abstract
Background: Due to the human need for food, any change in the quality and quantity of food will affect the health of the community. It is important to remove microbial contaminants from food during the production, storage and supply phases. In this study, the antibacterial effects of nanoparticles of zinc oxide on two Escherichia coli and Listeria monocytogenes were investigated.
Materials and Methods: In this study, zinc oxide nanoparticles were prepared from zeolite and quantified by X-ray fluorescence. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of nanoparticles of zinc oxide were determined using a disc diffusion method. Graphpad prism statistical software was used for data analysis and ANOVA was used for analysis of variance. Significant limit was set at 0.05 (P≤0.05).
Results: Based on the results of this study, the MIC value of nanoparticles of zinc oxide for all tested bacteria was 4 mg/ml, and the MBC values for standard strain and Escherichia coli isolates were 8 and 4 mg/ml, respectively. The standard strain and isolate of Listeria monocytogenes was calculated to be 4 mg/ml.
Conclusion: The present study showed that zinc oxide nanoparticles can be used as a deterrent against the pathogens of the materials and avoid contamination.
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