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Policy-making in the care, prevention, and treatment of chemotherapy-induced mucositis: A policy brief
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Reza Hosseiniara    , Sajjad Taghadosi * , Sadegh Zarei , Mohsen Taghadosi |
| Faculty of Dentistry, Kashan University of Medical Sciences, Kashan, Iran , sajadtaghadosi1379@kaums.ac.ir |
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Abstract: (38 Views) |
Oral mucositis, as a common and debilitating complication of chemotherapy, in addition to consequences such as severe pain, nutritional impairment, reduced quality of life, increased risk of infection, and interruptions in cancer treatment, also holds specific importance for dentists. These aspects include mucosal mucositis, disruption of the normal oral flora (including Candida overgrowth), and effects on hematopoietic cells, where the reduction of white blood cells and neutrophils (WBC and PMN) increases the risk of infection and underscores the necessity of monitoring platelet counts prior to dental procedures. This policy brief examines various dimensions of the problem, analyzes shortcomings in current approaches, and provides evidence-based recommendations for policymakers, health administrators, healthcare providers, and researchers. The primary emphasis is on the need for an integrated, multidisciplinary, and evidence-based approach encompassing primary prevention, complication management, and patient support. Focus is placed on the development and implementation of standardized clinical guidelines, integration of supportive care into the cancer treatment pathway, education of patients and healthcare staff, and enhancement of applied research for generating local evidence and evaluating intervention effectiveness.
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| Keywords: Mucositis, Chemotherapy, Cancer, Evidence-Based Medicine, Policy Brief |
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Type of Study: Policy Brief |
Subject:
General
Received: 2025/12/8 | Revised: 2026/02/3 | Accepted: 2026/01/14
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