One of the effective tools for identifying and preventing adverse transfusion reactions is the integration of clinical decision support systems with electronic health records. Although existing research in the field of hemovigilance highlights the potential value of these systems, challenges within policy and governance frameworks may hinder their effective integration and optimal use within electronic health records for managing Adverse Transfusion Reactions. The analysis presented in this policy brief is based on evidence derived from a systematic review conducted in 2025. Based on the collected data, nine key challenges related to the integration of these systems with electronic health records were identified, along with corresponding policy recommendations and the identification of relevant policymakers. To address these challenges, the development of a comprehensive national governance framework and the design of a long-term roadmap for integrating electronic health records with artificial intelligence based clinical decision support systems are recommended as priority actions.