[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 3, Issue 1 (Quaterly 1999) ::
Feyz 1999, 3(1): 57-63 Back to browse issues page
The effect of human blood groups on growth of the agent of Leishmaniasis
Gholam Reza Vali *, Safar Ali Talari
Abstract:   (8820 Views)

History and Objectives: Due to the prevalence and importance of diagnosis and treatment of Leishmaniasis in Iran and considering the difficulties and the economical burden of providing culture media from rabbit’s blood, this study was carried out to investigate the effects of human’s blood on growth of Leishmania and compare these with the rabbit’s blood culture media in Kashan in 1374.

Materials and Methods: An experimental study was performed on promastigote of L.major, L.tropica and L.infantum, approved by World Health Organization, on rabbit’s blood culture media and the 8 human’s blood culture media that 4 of these were repeated. The adaptability time to the medium, the maximal and minimal growth were calculated and statistically analyzed on the basis of the decrease in the number of active parasites from the time of culturing.

Results: The adaptability time was one to two days and was equal in both types of culture media, parasites on the human’s blood media achieved maximal growth in a shorter time than their counterparts on rabbit’s blood media and the minimum number of growth was higher on rabbit’s blood culture media. Number of parasites grow on rabbit’s blood were higher than human’s blood in all three types of parasites (P<0.05) and were higher in Rh negative than Rh positive and in blood group type B than the other ones.

Conclusion: Due to the importance of growth velocity of the parasite, rabbit’s blood can be replaced by human blood groups. Performing research on human specimens is recommended.

Full-Text [PDF 1039 kb]   (1485 Downloads)    
Type of Study: Research | Subject: General
Received: 2008/11/19 | Published: 1999/04/15
Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Vali G R, Talari S A. The effect of human blood groups on growth of the agent of Leishmaniasis . Feyz. 1999; 3 (1) :57-63
URL: http://feyz.kaums.ac.ir/article-1-528-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 3, Issue 1 (Quaterly 1999) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4422