History and Objectives: Infection is the most common complication and the main cause of mortality in burns and in different burn centers, there are various types of microbacteria producing infection with different drug resistance levels. In order to define the prevalence type of microorganism and drug resistance in burn wounds, this research was carried out in Injuries and Burn hospital of Kerman in 1376.

Materials and Methods: A descriptive study was performed on 110 burned patients by wound biopsy, microbial culture and antibiogram.

Results: The most common isolated microbacteria as the etiologic agent of wound infection were Pseudomonas (35.5%), Klebsiella (14.5%) and Staphylococcus aureus (8.2%). On evaluation for drug sensitivity of the microbacteria, Ciprofloxacin was found to be the most effective drug against Pseudomonas and Klebsiella and Vancomycin the most effective one for Staphylococcus aureus.

Conclusion: Pseudomonas, Klebsiella and Staphylococcus aureus are the most important microorganisms in the burn wounds. Accurate treatment of the burned wound should be performed by biopsy, cultured and antibiogram