History and Objectives: Trichomoniasis is one of the sexual diseases of the urogenital system with multiple known complications. Due to the various prevalence of this parasite in this country and the large number of asymptomatic patients, a research was performed at family planning and clinics of gynecology in Kashan in order to define the prevalence of trichomoniasis and the role of effective factors in the development of this disease in 1372 and 1373.

Materials and Methods: A descriptive study was performed on 900 women. Infestation with trichomoniasis was defined as positive results on wet smear, or modified Diamond culture, Dorset’s culture and Papanicolaou staining. The role of age, educational level, pH, signs and symptoms of the disease and the prevention methods of pregnancy in the development of the disease was determined. Results were presented by using descriptive statistics.

Results: The prevalence of infestation with Trichomonas vaginalis was 2.1% (19 patients) and with a 95% confidence interval, the prevalence of infestation was estimated as at least 1% and at most 3% in the general populations. Trichomoniasis was most commonly observed at pH of 5.6 to 6 in house keeper, illiterate women of 20 to 34 years old. No significance correlation was found between age, occupation, level of knowledge, pH, clinical manifestations (Pruritus, burning sensation, painful intercourse) and the methods of prevention of pregnancy on one side and the rate of infestation on the other side.

Conclusion: The prevalence of trichomoniasis is relatively low in Kashan and its clinical manifestation is not pathognomonic. Correct diagnosis by using laboratory methods and appropriate treatment is recommended.