[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 27, Issue 1 (Bimonthly 2023) ::
Feyz 2023, 27(1): 67-75 Back to browse issues page
The effect of two month high-intensity interval training and vitamin D supplementation on the blood levels of homocysteine and total antioxidant capacity in overweight women with vitamin D deficiency. A clinical trial study
Amir Nosrati , Babisan Askari , Masoumeh Habibian
Department of Physical Education and Sports Sciences, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran , babisan.askari@gmail.com
Abstract:   (708 Views)
Background: One of the important goals of therapeutic interventions is to control obesity and vitamin D deficiency, which are associated with the occurrence of cardiovascular disease, metabolic disorders and increased homocysteine. In this study, the effect of high-intensity interval resistance training (HIIRT) and vitamin D on homocysteine and total antioxidant capacity (TAC) ​​levels in overweight women with vitamin D deficiency was investigated.
Materials and Methods: In this clinical trial study, overweight women with vitamin D deficiency were investigated. The subjects were randomly divided into four groups of 13 (control, exercise, vitamin D and exercise+vitamin D). The exercise groups performed HIIRT with an intensity of 80% of one maximum repetition, and the vitamin D groups consumed vitamin D once a week. The collected data were analyzed using one-way analysis of variance and paired t-tests.
Results: After 8 weeks of research interventions, homocysteine level decreased and TAC significantly increased in the experimental groups (P<0.001). In addition, combined intervention was associated with more changes in homocysteine and TAC levels compared to HIIRT and vitamin D intervention (P<0.001), but HIIRT and vitamin D had a similar effect on the changes of these variables (P>0.05).
Conclusion: It seems that part of the optimal effects of HIIRT and vitamin D consumption in the health development of overweight women with vitamin D deficiency can be induced by increasing TAC and decreasing homocysteine.
Keywords: High-intensity interval training, Homocysteine, Overweight, Total antioxidant capacity, Vitamin D
Full-Text [PDF 353 kb]   (322 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2022/07/27 | Revised: 2023/07/25 | Accepted: 2023/01/2 | Published: 2023/04/5
References
1. Duan L, Han L, Liu Q, Zhao Y, Wang L, Wang Y. Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations. Ann Nutr Metab 2020; 76(3): 153-64.
2. Bassatne A, Chakhtoura M, Saad R, Fuleihan GE. Vitamin D supplementation in obesity and during weight loss: A review of randomized controlled trials. Metabolism 2019; 92: 193–205.
3. Verdoia M, Nardin M, Gioscia R, Saghir Afifeh AM, Viglione F, Negro F, et al. Association between vitamin D deficiency and serum Homocysteine levels and its relationship with coronary artery disease. J Thromb Thrombolysis 2021; 52(2): 523-31.
4. Glueck CJ, Jetty V, Rothschild M, Duhon G, Shah P, Prince M, et al. Associations between serum 25-hydroxyvitamin D and lipids, lipoprotein cholesterols, and homocysteine. N Am J Med Sci 2016; 8(7): 284–90.
5. Troen AM. The central nervous system in animal models of hyperhomocysteinemia. Prog Neuropsychopharmacol Biol Psych 2005; 29: 1140-51.
6. Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002; 325: 1202.
7. Wang J, You D, Wang H, Yang Y, Zhang D, Lv J, et al. Association between homocysteine and obesity: A meta-analysis. J Evid Based Med 2021; 14(3): 208-17.
8. Nedelcu C, Ionescu M, Pantea-Stoian A, Niţă D, Petcu L, Mazilu L, et al. Correlation between plasma homocysteine and first myocardial infarction in young patients: Case-control study in Constanta County, Romania. Exp Ther Med 2021; 21(1): 101.
9. Baser H, Can U, Baser S, Hidayetoglu BT, Aslan U, Buyuktorun I, et al. Serum total oxidant/anti-oxidant status, ischemia-modified albumin and oxidized-low density lipoprotein levels in patients with vitamin D deficiency. Arch Endocrinol Metab 2015; 59(4): 318-24.
10. Choromańska B, Myśliwiec P, Łuba M, Wojskowicz P, Myśliwiec H, Choromańska K, et al. Impact of Weight Loss on the Total Antioxidant/Oxidant Potential in Patients with Morbid Obesity-A Longitudinal Study. Antioxidants (Basel) 2020; 9(5): 376.
11. van der Schaft N, Schoufour JD, Nano J, Kiefte-de Jong JC, Muka T, Sijbrands, et al. Dietary antioxidant capacity and risk of type 2 diabetes mellitus, prediabetes and insulin resistance: The Rotterdam Study. Eur J Epidemiol 2019; 34: 853-61.
12. Halalkhor F. Effect of Flaxseed Supplementation and Concurrent Physical Activity on Total Antioxidant Capacity of the Plasma and the Lipid Peroxidation Index of Overweight Women. J Med Plants 2019; 18 (70):144-153.
13. Attarzadeh Hosseini SR, Moazzami M, Farahati S, Bahremand M, Sadegh Eghbali F. Effects of High-Intensity Interval Training versus Moderate-Intensity Continuous Training on the Total Antioxidant Capacity, Malondialdehyde, and Superoxide Dismutase in Obese/Overweight Middle-Aged Women. Iran J Endocrinol Metab 2020; 22(3): 207-13. [in Persian]
14. Emamdoost S, Faramarzi M, Bagheri L, Otadi K, Razaghi Naeeni E, Yazdani T, et al . The effect of concurrent resistance and aerobic training on serum level of homocysteine and lipid profile in overweight men. SJKU 2015; 2(1): 80-8. [in Persian]
15. Soori R, Choopani S, Falahian N, Ramezankhani A. Effect of Physical Activity on Serum Homocysteine Levels in Obese and Overweight Women. Intern Med Today 2016; 22 (4): 307-12.
16. Atakan MM, Li Y, Koşar ŞN, Turnagöl HH, Yan X. Evidence-Based Effects of High-Intensity Interval Training on Exercise Capacity and Health: A Review with Historical Perspective. Int J Environ Res Public Health 2021; 18(13): 7201.
17. Hemati Nafar M, Tolouei Azar J, Behnam M. Homocysteine and lipid profile response in sedentary young men to six weeks high intensity interval training. Sport Sci 2017; 10 (Suppl 1): 111-16.
18. Roh HT, Cho SY, So WY. A Cross-Sectional Study Evaluating the Effects of Resistance Exercise on Inflammation and Neurotrophic Factors in Elderly Women with Obesity. J Clin Med 2020; 9(3): 842.
19. Moro T, Marcolin G, Bianco A, Bolzetta F, Berton L, Sergi G, et al. Effects of 6 Weeks of Traditional Resistance Training or High Intensity Interval Resistance Training on Body Composition, Aerobic Power and Strength in Healthy Young Subjects: A Randomized Parallel Trial. Int J Environ Res Public Health 2020; 7(11): 4093.
20. Khodadoust M, Habibian M. Investigating the Changes of Tumor Necrosis Factor-α and Interleukin-10 After 8 Weeks of Regular Pilates Exercise and Vitamin D Intake in Overweight Men: A Randomized Clinical Trial. J Arak Uni Med Sci 2020; 23 (6): 888-901. [in Persian]
21. Sadeghi Shirsavar H, Habibian M, Farajtabar Behrestaq S. Effect of One Course of Pilates Training with Vitamin D supplement on Monocyte Chemoattractant Protein-1 Level and Superoxide Dismutase Activity in Overweight Men: A Clinical Trial Study. J Gorgan Univ Med Sci 2022; 24(1): 10-18.
22. Rekha S, Patel ML, Pooja G, Pushpalata S, Natu SM, Pradeep Y. Correlation of plasma homocysteine levels with BMI Insulin Resistance amongst Obese, Overweight and Non Obese Infertile Women. Int J Sci Res Publ 2012; 2(5): 1-6.
23. Besagil PS, Çalapkorur S, Şahin H. Determination of the relationship between total antioxidant capacity and dietary antioxidant intake in obese patients. Niger J Clin Pract 2020; 23(4): 481-88.
24. Asghari G, Yuzbashian E, Wagner CL, Park Y, Mirmiran P, Hosseinpanah F. Daily vitamin D3 in overweight and obese children and adolescents: a randomized controlled trial. Eur J Nutr 2021; 60(5): 2831-40.
25. Dabaghzadeh F, Rahimpour M, Karami-Mohajeri S. Effect of vitamin D administration on blood oxidative stress factors in university students: A randomized double-blind clinical trial. Koomesh 2021; 23 (6): 712-9. [in Persian]
26. Wimalawansa SJ. Vitamin D Deficiency: Effects on Oxidative Stress, Epigenetics, Gene Regulation, and Aging. Biology (Basel) 2019; 8(2): 30.
27. Herrmann W, Herrmann M. The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases. Nutrients 2022; 14(7): 1412.
28. Pham TM, Ekwaru JP, Mastroeni SS, Mastroeni MF, Loehr SA, Veugelers PJ. The Effect of Serum 25-Hydroxyvitamin D on Elevated Homocysteine Concentrations in Participants of a Preventive Health Program. PLoS One 2016; 11(8): e0161368.
29. Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, et al. 1,25-Dihydroxyvitamin D3influences cellular homocysteine levels in murine preosteoblastic MC3T3–E1 cells by direct regulation of cystathionine β-synthase. J Bone Miner Res 2011; 26(12): 2991–3000.
30. Mohammadyari S, Abdi S, Bakhtiyari A. The effect of low volume high-intensity interval training on predictive markers of cardiovascular disease in overweight men. SPMI 2019; 11(2): 133-43. [in Persian]
31. Wu G. Amino acids: metabolism function and nutrition. Amino Acids 2009; 37: 1–17.
32. Vincent KR, Braith RW, Bottiglieri T, Vincent HK, Lowenthal DT. Homocysteine and lipoprotein levels following resistance training in older adults. Prev Cardiol 2003; 6(4): 197-203.
33. Rodrigo R, Passalacqua W, Araya J, Orellana M, Rivera G. Implications of oxidative stress and homocysteine in the pathophysiology of essential hypertension. J Cardiovasc Pharmacol 2003; 42(4): 453-61.
34. Ghorbanian B, Azali Alamdari K, Saberi Y, Shokrrolahi F, Mohammadi H. Effect of an Incremental Interval Endurance Rope-training Program on Antioxidant Biomarkers and Oxidative Stress in Non-active Women. SJNMP 2018; 4(1): 29-40. [in Persian]
35. Amirkhani Z, Azarbayjani MA. Effect of eight weeks resistance training on malondialdehyd, total, antioxidant capacity, liver enzymes and lipid profile in overweight and obese women. J Gorgan Univ Med Sci 2018; 20(3): 48-55. [in Persian]
36. Fakhri S, Shakeryan S, Fakhri F, Alizadeh AA. The effect of 6 weeks of high-intensity interval training (HIIT) with using Nano-curcumin supplement on total antioxidant capacity and Malondialdehyde level in overweight girls. J Birjand Univ Med Sci 2019; 26(4): 333-42. [in Persian]
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nosrati A, Askari B, habibian M. The effect of two month high-intensity interval training and vitamin D supplementation on the blood levels of homocysteine and total antioxidant capacity in overweight women with vitamin D deficiency. A clinical trial study. Feyz 2023; 27 (1) :67-75
URL: http://feyz.kaums.ac.ir/article-1-4672-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 27, Issue 1 (Bimonthly 2023) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.04 seconds with 46 queries by YEKTAWEB 4645