[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 5, Issue 2 (Quarterly 2001) ::
Feyz 2001, 5(2): 32-38 Back to browse issues page
Immunohistochemical evaluation of Tenascin distribution in different stages of pulp development in mice
Tayyebe Kermani , Abdoreza Varasteh , Mohammad Reza Nikravesh , Tahere Talaie Khozani
Abstract:   (9455 Views)

History and Objectives: Morphogenesis is achieved by the effect of different tissue factors including mesenchymal-epithelial interaction, but its chemical basis is unknown. One of the most appropriate models is the mammalian tooth, especially its pulp. The phenomena migration, proliferation and differentiation within dental pulp are affected by the components of extracellular fluid. In this respect, tenascin is one of these components that is involved in the initial stages of development and differentiation of some fetal tissues including teeth and is important in the pathogenesis of tumors.

Materials and Methods: The present study was conducted on 40 ball-c mice. Different development stages of dental pulp were evaluated within the days 12-19, using immunohistochemical methods and monoclonal antibody against tenascin.

Results: The finding showed that at the bud stage, tenascin is found in the ectomesenchymal tissue and basement membrane of enamel organ in a high quantity and there is reduction in its level in cap stage. With developmental progression, the tenascin level increases significantly in early bell stage for pulp and in late bell stage in cortex.

Conclusion: Tenascin can play an important role in morphogenesis during development of pulp. In this respect, epithelial-mesenchymal interaction is very important. Therefore, it is recommended to conduct more studies to determine the role of tenascin in the differentiation oddentoblasts following injury.

Keywords: Pulp, Fetal development, Interaction
Full-Text [PDF 1773 kb]   (1590 Downloads)    
Type of Study: Research | Subject: General
Received: 2008/11/11 | Published: 2001/07/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kermani T, Varasteh A, Nikravesh M R, Talaie Khozani T. Immunohistochemical evaluation of Tenascin distribution in different stages of pulp development in mice . Feyz 2001; 5 (2) :32-38
URL: http://feyz.kaums.ac.ir/article-1-382-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 5, Issue 2 (Quarterly 2001) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.06 seconds with 46 queries by YEKTAWEB 4645