:: Volume 23, Issue 1 (Bimonthly 2019) ::
Feyz 2019, 23(1): 45-51 Back to browse issues page
Investigation of the bactriocin effect of lactic acid probiotic bacteria isolated from dairy products of Nadushan region, Yazd
Hassan Hassani-Bafrani , Monavareh Ahmadi , Gholam Reza Khosravi , Erfan Khosravi , Mohammad Karimian
Anatomical Research Center, Kashan University of Medical Sciences, Kashan, Iran , mdkarimian@gmail.com
Abstract:   (2806 Views)
Background: Among probiotics, lactobacillus species with bacteriocin activities have been used in microbial biotechnology as safe biological preservatives. So, this study aimed to determine antimicrobial activity of bacteriocins of lactobacillus species isolated from lactic acid bacteria in traditional dairy products.
Materials and Methods: In this experimental study, isolated lactic acid bacteria from local yoghurt of Nadushan region were used as probiotics with a bacteriocin production potential. The bacteriocin effect of isolated lactic acid bacteria was investigated against seven pathogenic bacteria using well diffusion and disk methods.
Results: The results of well diffusion analysis showed that the most growth inhibitory effect against Staphylococcus epidermidis, Escherichia coli Staphylococcus aureus, Enterococcus faecalis and Candida albicans pathogen bacteria was caused by isolated lactic acid bacteria including Lactobacillus delbrucki, Lactobacillus caesium and Lactobacillus plantarum, respectively. Also, the results of disc method showed that the highest inhibitory effect against the bacterial pathogens was caused by Lactobacillus delbrucki, Lactobacillus plantarum and Lactobacillus caesium, respectively. Although antimicrobial compounds were inactivated by proteolytic enzymes, they showed stability against variant pH and temperature treatments.
Conclusion: It seems that bacteriocin of the probiotics isolated from dairy products of this region can be used as a safe and healthy biological preservative in food industry.
Keywords: Lactobacillus, Bacteriocin, Pathogenic, Antimicrobial
Full-Text [PDF 368 kb]   (573 Downloads)    
Type of Study: Research | Subject: General
Received: 2018/09/12 | Revised: 2019/05/15 | Accepted: 2018/12/23 | Published: 2019/04/17
References
1. Buckwalter JA, Mankin HJ. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect 1998; 47: 487-504.
2. Glyn-Jones S, Palmer AJ, Agricola R, Price AJ, Vincent TL, Weinans H, et al. Osteoarthritis. Lancet 2015; 386(9991): 376-87.
3. Felson DT. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin Arthritis Rheum 1990; 20(3 Suppl 1): 42-50.
4. McCarthy GM, Cheung HS. Point: Hydroxyapatite crystal deposition is intimately involved in the patho-genesis and progression of human osteoarthritis. Curr Rheumatol Rep 2009; 11(2): 141-7.
5. Blanco FJ. Osteoarthritis: something is moving. Reumatol Clin 2014; 10(1): 4-5.
6. Abramson SB, Attur M. Developments in the scientific understanding of osteoarthritis. Arthritis Res Ther 2009; 11(3): 227.
7. Yin YW, Sun QQ, Hu AM, Wang Q, Liu HL. Asso‌ciation of rs9340799 polymorphism in estrogen receptor alpha gene with the risk of osteoarthritis: evidence based on 8,792 subjects. Mol Genet Genomics 2015; 290(2): 513-20.
8. [8] Brandt KD, Dieppe P, Radin E. Etiopathogenesis of osteoarthritis. Med Clin NorthMed Clin North Am 2009; 93(1): 1-24.
9. Bastick AN, Runhaar J, Belo JN, Bierma-Zeinstra SM. Prognostic factors for progression of clinical osteo-arthritis of the knee: a systematic review of obser‌vational studies. Arthritis Res Ther 2015; 17(1): 152.
10. Davis MA, Ettinger WH, Neuhaus JM, Cho SA, Hauck WW. The association of knee injury and obesity with unilateral and bilateral osteoarthritis of the knee. Am J Epidemiol 1989; 130(2): 278-88.
11. Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Role of proinflammatory cyto‌kines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011; 7(1): 33-42.
12. Kolls JK, Lindén A. Interleukin-17 family mem‌bers and inflammation. Immunity 2004; 21(4): 467-76.
13. Alsalameh S, Mollenhauer J, Hain N, Stock KP, Kalden JR, Burmester GR. cellular immune response to and human articular chondrocytes t cell reactivities against chondrocyte and fibroblast membranes in des‌tructive joint diseases. Arthritis Rheum 1990; 33(10): 1477-86.
14. Maione F. IL-17 in Chronic Inflammation: From Discovery to Targeting. Front Pharmacol 2016; 7: 250.
15. Koshy PJ, Henderson N, Logan C, Life PF, Cawston TE, Rowan AD. Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines. Ann Rheum Dis 2002; 61(8): 704-13.
16. Kim YG, Park JW, Lee JM, Suh JY, Lee JK, Chang BS, et al. IL-17 inhibits osteoblast differentiation and bone regeneration in rat. Arch Oral Biol 2014; 59(9): 897-905.
17. Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999; 103(9): 1345-52.
18. Chu CR, Szczodry M, Bruno S. Animal models for cartilage regeneration and repair. Tissue Eng Part B Rev 2010; 16(1): 105-15.
19. Pelletier JP, Martel-Pelletier J, Abramson SB. Ost‌e‌o‌‌arthritis, an inflammatory disease: potential impl‌ic‌ation for the selection of new therapeutic targets. Arthritis Rheum 2001; 44(6): 1237-47.
20. Guilak F. Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheumatol 2011; 25(6): 815-23.
21. Valdes AM, Spector TD. The contribution of genes to osteoarthritis. Rheum Dis Clin North Am 2008; 34(3): 581-603.
22. Loughlin J. The genetic epidemiology of human primary osteoarthritis: current status. Expert Rev Mol Med 2005; 7(9): 1-12.
23. Han L, Lee HS, Yoon JH, Choi WS, Park YG, Nam SW, et al. Association of IL- 17A and IL-17F single nucleotide polymorphisms with susceptibility to osteoarthritis in a Korean population. Gene 2014; 533(1): 119-22.
24. Goldring MB, Otero M. Inflammation in osteo‌arthritis. Curr Opin Rheumatol 2011; 23(5): 471-8.
25. Berenbaum F, Eymard F, Houard X. Osteoarthritis, inflammation and obesity. Curr Opin Rheumatol 2013; 25(1): 114-8.
26. Bondeson J, Blom AB, Wainwright S, Hughes C, Caterson B, van den Berg WB. The role of synovial macrophages and macrophage‐produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis Rheum 2010; 62(3): 647-57.
27. Zhang Y, Pizzute T, Pei M. Anti-inflammatory strategies in cartilage repair. Tissue Eng Part B Rev 2014; 20(6): 655-68.
28. Wojdasiewicz P, Poniatowski ŁA, Szukiewicz D. The role of inflammatory and anti-inflammatory cyto‌kines in the pathogenesis of osteoarthritis. Mediators Inflamm 2014; 2014: 561459.
29. Berenbaum F. Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!). Osteoarthritis Cartilage 2013; 21(1): 16-21.
30. Miljkovic D, Trajkovic V. Inducible nitric oxide synthase activation by interleukin-17. Cytokine Growth Factor Rev 2004; 15(1): 21-32.
31. Zamani-Badi T, Nikzad H, Karimian M. IL-1RA VNTR and IL-1α 4845G>T polymorphisms and risk of idiopathic male infertility in Iranian men: A case-control study and an in silico analysis. Andrologia 2018; 50(9): e13081.
32. Nejati M, Atlasi MA, Karimian M, Nikzad H, Azami Tameh A. Lipoprotein lipase gene poly‌mo‌r‌ph‌is‌ms as risk factors for stroke: a computational and meta-analysis. Iran J Basic Med Sci 2018; 21(7): 701-8.
33. Karimian M, Aftabi Y, Mazoochi T, Babaei F, Khamechian T, Boojari H, et al. Survivin poly‌mor‌phisms and susceptibility to prostate cancer: A genetic association study and an in silico analysis. EXCLI J 2018; 17: 479-91.
34. Noureddini M, Mobasseri N, Karimian M, Behjati M, Nikzad H. Arg399Gln substitution in XRCC1 as a prognostic and predictive biomarker for prostate cancer: evidences from 8662 subjects and a structural analysis. J Gene Med 2018; 20(10-11): e3053.
35. Zamani-Badi T, Karimian M, Azami-Tameh A, Nikzad H. Association of C3953T transition in inter‌leukin 1β gene with idiopathic male infertility in an Iranian population. Hum Fertil (Camb) 2017; 1-7.
36. Mobasseri N, Nikzad H, Karimian M. Protective effect of estrogen receptor α-PvuII transition against idiopathic male infertility: A case-control study and meta-analysis. Reprod Biomed Online 2019; pii: S1472-6483(19)30058-6.
37. Tameh AA, Karimian M, Zare-Dehghanani Z, Aftabi Y, Beyer C. Role of Steroid Therapy after Ischemic Stroke by n-Methyl-d-Aspartate Receptor Gene Regulation. J Stroke Cerebrovasc Dis 2018; 27(11): 3066-75.

XML   Persian Abstract   Print

Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 23, Issue 1 (Bimonthly 2019) Back to browse issues page