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:: Volume 20, Issue 6 (Bimonthly 2017) ::
Feyz 2017, 20(6): 518-524 Back to browse issues page
Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery
Fatemeh Hasanshiri , Mohammad Sadegh Pourabbasi , Seyyed Gholam Abbas Mousavi , Mojdeh Fatahi , Amir Abbas Kianfar , Hamid Reza Seyedi , Fakhrosadat Mirhoseini , Mehrdad Mahdian
Department of Heart, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, I. R. Iran. , drmpourabbasi@yahoo.com
Abstract:   (6355 Views)

Background: Increased serum lactate during cardio-pulmonary bypass is associated with high mortality and cardiac complications up to 10-20 percent. The aim of this study was to evaluate the effect of serum lactate increase on postoperative outcomes after coronary artery bypass graft (CABG) Surgery.

Materials and Methods: This descriptive-analytical study was performed on cases (no=116) undergoing CABG at Beheshti hospital in Kashan between 2013-2014. Demographic data, variables related to surgery, serum lactate level and the time of tracheal extubation, length of stay in intensive care unit (ICU) and hospital post-surgery left ventricular ejection fraction were collected. These data was compared in two groups: Normal serum lactate (< 2 m molliter) and Hyperlactatemia (> 2 m molliter) group.

Results: The postoperative hyperlactatemia was observed in 62.1 % of patients. There were no significant differences between two groups in time of tracheal extubation, length of stay in ICU and hospital. There was a relationship between the mean postoperative serum lactate and blood sugar, bicarbonate, pH, length of cardiopulmonary bypass and the aortic cross clamping time. There was a significant relationship between the serum lactate increment and the left ventricular ejection fraction decrement.

Conclusion: Hyperlactatemia is probably associated with such important factors as high blood sugar, longer duration of aortic cross clamp and cardio-pulmonary bypass time. So controlling such factors can reduce the rate of hyperlactatemia and help postoperative recovery.

Keywords: Coronary artery bypasses graft, Serum lactate, Cardiopulmonary bypass, Postoperative outcomes
Full-Text [PDF 224 kb]   (2293 Downloads)    
Type of Study: Research | Subject: General
Received: 2017/01/2 | Revised: 2017/07/24 | Accepted: 2017/01/2 | Published: 2017/01/2
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Hasanshiri F, Pourabbasi M S, Mousavi S G A, Fatahi M, Kianfar A A, Seyedi H R, et al . Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery . Feyz 2017; 20 (6) :518-524
URL: http://feyz.kaums.ac.ir/article-1-3225-en.html


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Volume 20, Issue 6 (Bimonthly 2017) Back to browse issues page
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