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:: Volume 20, Issue 6 (Bimonthly 2017) ::
Feyz 2017, 20(6): 495-500 Back to browse issues page
Effects of noise stress on serum level of cortisol and anxiety in male rats
Rahim Ahmadi, Parisa Tavakoli, Ozra Tavakoli *
Department of Psychology, Faculty of Educational Sciences, Payam Noor University, Mallard Branch, Tehran, I. R. Iran. , M.tavakolli59@yahoo.com
Abstract:   (2505 Views)

Background: Studies show that there is an association between noise pollution and psychological/physical diseases. The main aim of this study was to determine the effects of noise stress on serum level of cortisol and changes of anxiety level in male rats.

Materials and Method: In our study male Wistar rats were randomly divided into control, exposed (noise stress for 1h, 3h, and 6h/day) groups. After 8 weeks, blood samples were obtained using cardiac puncture and after serum preparation, cortisol level was measured using ELISA. In addition for the evaluation of anxiety elevated plus maze was used in the last week of the experiment.

Results: The results indicated an increased serum cortisol level in rats exposed to noise stress for 1h,3 h/day compared to control (P<0.05). However serum cortisol level of in rats exposed to noise stress for 6 h/day showed no significant difference. In addition, the results of the elevated plus maze showed that percentage of time spent in open arms was significantly decreased in all experimental groups compared to control (P<0.001). Moreover, a significant  decrease in the percentage number of entries into open arms compared to the control was observed in all experimental groups (P<0.001).

Conclusions: Our findings show that exposure to noise stress can reduce the adrenal cortex function which is proportionally related to enhanced anxiety level.

Keywords: Noise stress, Cortisol, Anxiety, Elevated plus Maze, Rat
Full-Text [PDF 248 kb]   (1235 Downloads)    
Type of Study: Research | Subject: General
Received: 2017/01/1 | Accepted: 2017/01/1 | Published: 2017/01/1
1. Goss CH, Newsom SA, Schildcrout JS, Sheppard L, Kaufman JD. Effect of ambient air pollution on pulmonary exacerbations and lung function in cystic fibrosis. Am J Respir Crit Care Med 2004; 169(7): 816-21.
2. Pintérné E, editor. Light Pollution and its Effect on the Living World. International Scientific Conference on Sustainable Development & Ecological Footprint Sopron, Hungary; 2012.
3. Sumartono S. Visual Pollution in the Context of Conflicting Design Requirements. J Visual Art Design 2009; 3(2): 187-96.
4. Stansfeld SA, Matheson MP. Noise pollution: non-auditory effects on health. Br Med Bull 2003; 68(1): 243-57.
5. Fullick A. Edexcel International GCSE Biology,Edexcel Certificate in Biology: Revision Guide 2011.
6. Singh N, Davar SC. Noise pollution-sources, effects and control. J Hum Ecol 2004; 16(3): 181-7.
7. Hogan CM, Latshaw GL. The relationship between highway planning and urision specialty conference, May 21-23, 1973, Chicago, Illinois. by American Society of Civil Engineers. Urban Transportation Division.
8. Geen RG, McCown EJ. Effects of noise and attack on aggression and physiological arousal. Motivation Emotion1984; 8(3): 231-41.
9. Abbate C, Concetto G, Fortunato M, Brecciaroli R, Tringali MA, Beninato G, et al. Influence of environmental factors on the evolution of industrial noise-induced hearing loss. Environ Monit Assess 2005; 107(1-3): 351-61.
10. Krebs H, Macht M, Weyers P, Weijers HG, Janke W. Effects of stressful noise on eating and non-eating behavior in rats. Appetite 1996; 26(2): 193-202.
11. Skånberg A. Road traffic noise-induced sleep disturbances: a comparison between laboratory and field settings. J Sound Vibration 2004; 277(3): 465-7.
12. Martin PR, Reece J, Forsyth M. Noise as a trigger for headaches: relationship between exposure and sensitivity. Headache 2006; 46(6): 962-72.
13. Bigert C, Bluhm G, Theorell T. Saliva cortisol–a new approach in noise research to study stress effects. Int J Hyg Environ Health 2005; 208(3): 227-30.
14. Windle R, Shanks N, Lightman SL, Ingram CD. Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats 1. Endocrinology 1997; 138(7): 2829-34.
15. Rosen S, Olin P. Hearing loss and coronary heart disease. Arch Otolaryngol 1965; 82(3): 236-43.
16. Fields JM. Effect of personal and situational variables on noise annoyance in residential areas. J Acoustical Society Am 1993; 93(5): 2753-63.
17. Hemadi M, Saki G, Rajabzadeh A, Khodadadi A, Sarkaki A. The effects of honey and vitamin E administration on apoptosis in testes of rat exposed to noise stress. J Human Reproductive Sci 2013; 6(1): 54.
18. Gorai AK, Pal AK. Noise and its effect on human being--a review. J Environ Sci Engineering 2006; 48(4): 253-60.
19. Goodman H. Adrenal glands. Basic Medical Endocrinology. 2003: 112-20.
20. Van Dijk F, Souman A, De Vries F. Non-auditory effects of noise in industry. Int Arch Occup Environ Health 1987; 59(2): 133-45.
21. Heinonen-Guzejev M, Koskenvuo M, Mussalo-Rauhamaa H, Vuorinen HS, Heikkilä K, Kaprio J. Noise sensitivity and multiple chemical sensitivity scales: Properties in a population based epidemiological study. Noise Health 2012; 14(60): 215.
22. Pascuan CG, Uran SL, Gonzalez-Murano MR, Wald MR, Guelman LR, Genaro AM. Immune alterations induced by chronic noise exposure: comparison with restraint stress in BALB/c and C57Bl/6 mice. J Immunotoxicol 2014; 11(1): 78-83.
23. Rabat A, Bouyer J, George O, Le Moal M, Mayo W. Chronic exposure of rats to noise: relationship between long-term memory deficits and slow wave sleep disturbances. Behav Brain Res 2006; 171(2): 303-12.
24. Naqvi F, Haider S, Perveen T, Haleem DJ. Sub-chronic exposure to noise affects locomotor activity and produces anxiogenic and depressive like behavior in rats. Pharmacol Reports 2012; 64(1): 64-9.
25. Kesari KK, Siddiqui MH, Meena R, Verma H, Kumar S. Cell phone radiation exposure on brain and associated biological systems 2013.
26. Stansfeld S, Gallacher J, Babisch W, Shipley M. Road traffic noise and psychiatric disorder: prospective findings from the Caerphilly Study. BMJ 1996; 313(7052): 266-7.
27. Eriksson C, Nilsson ME, Willers SM, Gidhagen L, Bellander T, Pershagen G. Traffic noise and cardiovascular health in Sweden: The roadside study. Noise Health 2012; 14(59): 140.
28. Sood S, Narang D, Thomas MK, Gupta YK, Maulik SK. Effect of Ocimum sanctum Linn. on cardiac changes in rats subjected to chronic restraint stress. J Ethnopharmacol 2006; 108(3): 423-7.
29. [29] Sarkaki A, Heydari A, Shahraki MR. Effects of noise stress during fetal life on pain threshold in rats. J Kerman Univ Med Sci 2000; 7(2): 53-9. [in Persian]
30. Institute of Laboratory Animal Resources (US). Committee on Care, Use of Laboratory Animals, National Institutes of Health (US). Division of Research Resources. Guide for the care and use of laboratory animals. National Academies; 1985.
31. Cui B, Wu M, She X, Liu H. Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain Res 2012; 1427: 35-43.
32. Ghotbi MR, Khanjani N, Barkhordari A, Moghadam SR, Mozaffari A, Gozashti MH. Changes in urinary catecholamines in response to noise exposure in workers at Sarcheshmeh Copper Complex, Kerman, Iran. Environ Monit Assess 2013; 185(11): 8809-14.
33. Carrasco GA, Van de Kar LD. Neuroendocrine pharmacology of stress. Eur J Pharmacol 2003; 463(1): 235-72.
34. Demirel R, Mollaoğlu H, Yeşilyurt H, Üçok K, Ayçiçek A, Akkaya M, et al. Noise induces oxidative stress in rat. Eur J General Med 2009; 6(1).
35. Tomei F, Rosati MV, Baccolo TP, Bernardini A, Ciarrocca M, Tomao E. Plasma concentration of adrenocorticotropic hormone in traffic policemen. J Occupational Health 2003; 45(4): 242-7.
36. Holgers KM, Juul J. The suffering of tinnitus in childhood and adolescence: El malestar por tinnitus en la niñez y en la adolescencia. Int J Audiol 2006; 45(5): 267-72.
37. Jauregui-Huerta F, Ruvalcaba-Delgadillo Y, Garcia-Estrada J, Feria-Velasco A, Ramos-Zuñiga R, Gonzalez-Perez O, et al. Early exposure to noise followed by predator stress in adulthood impairs the rat’s re-learning flexibility in Radial Arm Water Maze. Neuro Endocrinol Lett 2010; 31(4).
38. Seidman MD, Standring RT. Noise and quality of life. Int J Environ Res Public Health 2010; 7(10): 3730-8.
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Ahmadi R, Tavakoli P, Tavakoli O. Effects of noise stress on serum level of cortisol and anxiety in male rats. Feyz. 2017; 20 (6) :495-500
URL: http://feyz.kaums.ac.ir/article-1-3222-en.html

Volume 20, Issue 6 (Bimonthly 2017) Back to browse issues page
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