[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 19, Issue 2 (Bimonthly 2015) ::
Feyz 2015, 19(2): 154-161 Back to browse issues page
Comparing carotid intima-media thickness between the type 1 diabetes mellitus and healthy individuals
Fatemeh Jafari , Kobra Shiasi-Arani , Hamid Reza Talari , Farbod Talebian , Seyyed Peyman Khamechi , Hasan Nekoinejad , Hosein Akbari
Kashan University of Medical Sciences , kobra.shiasi@yahoo.com
Abstract:   (5195 Views)

Background: Increased carotid intima-media thickness (CIMT) is considered as a marker for early detection of atherosclerotic changes in the arterial walls. The purpose of this study was to assess CIMT in type 1 diabetic patients compared to controls.

Materials and Methods: A case-control study was performed on 34 patients with type 1diabetes mellitus and 33 healthy people in Kashan during 2013-2014. The inclusion criterion was the diabetes history more than one year and the exclusion criteria were the use of antihypertensive or lipid reducing drugs, smoking, family history of cardiovascular disease, any complications of diabetes and any chronic disease. The weight, height, blood pressure and CIMT of the patients were measured. Moreover, laboratory tests including fast blood sugar, Hb A1c and lipid tests were performed.

Results: Sixty-seven subjects (34 type 1 diabetes patients and 33 healthy controls) were evaluated. The mean history of diabetes mellitus was 76.03±51.44 months. The mean age of the healthy subjects was 15.35±5.73 years and for the patients 15.25±7.94 years. Mean CIMT in healthy subjects was 0.439±0.06 mm and in patients 0.478±0.05 mm (P=0.005). Moreover, maximum CIMT was higher in the patients than in the controls (P=0.01). The multiple linear regression showed that CIMT was about 0.012 units higher in diabetic patients than in controls, and also CIMT was increased 0.012 units per one unit increase in HbA1c values.

Conclusion: The mean CIMT in patients with type 1diabetes was higher than in the controls and positively correlated with the history of diabetes, while it does not correlate with the lipid profiles, blood pressure and body mass index.

Keywords: Diabetes mellitus, Intima media thickness, HbA1c, Arthrosclerosis
Full-Text [PDF 201 kb]   (1490 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2015/05/19 | Revised: 2015/06/1 | Accepted: 2015/05/19 | Published: 2015/05/19
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jafari F, Shiasi-Arani K, Talari H R, Talebian F, Khamechi S P, Nekoinejad H et al . Comparing carotid intima-media thickness between the type 1 diabetes mellitus and healthy individuals. Feyz 2015; 19 (2) :154-161
URL: http://feyz.kaums.ac.ir/article-1-2631-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 19, Issue 2 (Bimonthly 2015) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.05 seconds with 46 queries by YEKTAWEB 4645