Background: Burger disease is a relative common problem. The present study was conducted to determine the clinical features of Burger disease in patients referring to Taleghani hospital between 2000 and 2001.

Materials and Methods: It was a descriptive study. Diagnosis was made according to the clinical manifestations and angiographic studies. Finally, clinical features, and other demographic characteristics were recorded and analyzed using descriptive statistics.

Results: There was 42 patients with Burger disease, all of whom were male with the mean (±SD) age of 35.9±2 years. All of the subjects were smokers. 71% were addicted and 54.8% have been smoking for 10-20 years. 77.3% had low educational level and 69% were belonged to low-health status class. Pain on rest (81%), ischemic ulcer, claudication, gangrene, migrating thrombophlebitis, and upper limb pain were the most common symptoms.

Conclusion: Our study revealed different clinical profile as compared to western societies. Low socioeconomic status is associated with greater risk of Burger disease. Further studies are highly suggested.