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:: Volume 17, Issue 4 (Bimonthly 2013) ::
Feyz 2013, 17(4): 352-358 Back to browse issues page
Effect of Coriandrum sativum seed extract on the signs of allergic rhinitis
Sorosh Amani-Geshnigani *, Gholam Reza Shabanian
Shahrekord Universtiy of Medical Sciences , Soamani2008@yahoo.com
Abstract:   (9860 Views)

Background: Allergic rhinitis is an IgE-mediated inflammatory disorder of the nose induced after an allergen exposure. Coriander (Coriandrum sativum) is a member of Apiaceae family. Since the anti-inflammatory effect of this plant has been pharmacologically confirmed, this study aimed to examine the effect of C. sativum seeds on allergic rhinitis.

Materials and Methods: In this clinical trial study, patients with allergic rhinitis referred to Shahrekord ENT clinic were allocated into the case and control groups (n=36 in each group). Both groups underwent routine treatment procedures (i.e. cetirizine, nasoflow spray, daily nasal washing, and allergen avoidance). The case group was also treated with C. sativum seed extract (10-15 drops of Coriander spray, three times a day). All subjects were asked to fill out the questionnaire of the disease signs on the first, third, and seventh day of treatment.

Results: Results indicated that there was no significant difference between the two groups in the disease signs on the first day. On the third day nasal obstruction, conjunctivitis, and itchy eyes in the case group were significantly mild compared to the control group (P < 0.05). On the seventh day, rhinorrhea, conjunctivitis, and itchy eyes in the case group were significantly mild compared to the control group (P<0.05).

Conclusion: C. sativum seed extract can have a positive and curative effect on rhinorrhea, nasal obstruction, and itchy eyes therefore, it can be recommended as one of the efficacious medicinal plants for treatment of allergic rhinitis.

Keywords: C. sativum, Allergic rhinitis, Anti-inflammatory property
Full-Text [PDF 267 kb]   (1894 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2013/08/21 | Accepted: 2013/09/4 | Published: 2013/09/4
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Amani-Geshnigani S, Shabanian G R. Effect of Coriandrum sativum seed extract on the signs of allergic rhinitis . Feyz. 2013; 17 (4) :352-358
URL: http://feyz.kaums.ac.ir/article-1-2020-en.html


Volume 17, Issue 4 (Bimonthly 2013) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
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