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:: Volume 16, Issue 3 (Bimonthly 2012) ::
Feyz 2012, 16(3): 248-253 Back to browse issues page
Survival rate among children with acute lymphoblastic leukemia based on their relapse status in Shiraz Shahid Faghihi hospital during 2004-9
Amir Almasi-Hashiani , Soheila Zareifar , Akbar Hashemi-Teir
Arak University of Medical Sciences , amiralmasi@arakmu.ac.ir
Abstract:   (7046 Views)

Background: Relapse in leukemic patients is considered as a major cause of treatment failure and a decrease in patient survival rate. This study was conducted to determine the survival rate of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) based on their relapse status.

Materials and Methods: This retrospective cohort study was performed on a total of 243 cases of leukemia aged less than 15 years in Shiraz Shahid Faghihi hospital. Data were analyzed using Kaplan-Meier method, log-rank test and Cox regression model.

Results: The 1- and 5-year survival rates for patients without relapsed leukemia were 96.9 and 76.9% and for relapsed leukemia were 82.4 and 28.6%, respectively. Therefore, there was a significant relationship between the relapse occurrence and survival rate among the patients (P=0.001).

Conclusion: The relapse occurrence is one of the main effective factors in survival rate of leukemic patients a five-year survival rate in the patients is less than 30 percent in this center.

Keywords: Acute lymphoblastic leukemia, Acute myeloblastic leukemia, Relapse, Survival rate
Full-Text [PDF 220 kb]   (4974 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2012/05/21 | Revised: 2012/06/11 | Published: 2012/05/15
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Almasi-Hashiani A, Zareifar S, Hashemi-Teir A. Survival rate among children with acute lymphoblastic leukemia based on their relapse status in Shiraz Shahid Faghihi hospital during 2004-9. Feyz 2012; 16 (3) :248-253
URL: http://feyz.kaums.ac.ir/article-1-1485-en.html


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Volume 16, Issue 3 (Bimonthly 2012) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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